Well situated in a calm street, this little hotel is one for the individualist. The owners care for their guests, breakfast is excellent and our room was really nice and comfortable. more

I stayed at The 21 with several friends, Matt and Andy made us so welcome and the standard of accomodation was excellent. There are some great restaurants nearby and we were in walking distance of all the fab shops! I would not hesitate to stay here again. more

We have just returned from a girls reunion weekend staying at The Twenty-One, and I just wanted to let everyone know that all the great reviews are true! Amazingly personal service with the owners always on hand with restaurant recommendations and ideas of places to go/things to see/etc. Plus the full English breakfast was one of the best I have... more

Booked this place out of curiousity after reading rave reviews on Trip Advisor. It definitely exceeded our expectations - the best B&B we have ever stayed in. The rooms are spotlessly clean, tastefully decorated, and pretty quiet. Matt and Andy are very welcoming and shared lots of tips on what to see in Brighton & suggested great restaurants and bars.... more

We stayed at The Twenty One a couple of weeks ago and haven't stopped raving about it since. Matt and Andy were amazing - attentive, generous with their time and full of great suggestions for restaurants and places to go. They made our 5th anniversary incredibly special. The Hotel is gorgeous with everything you could want. Thank you so much... more

21st September 2008. Just returned from a fantastic four night stay. The '21' is a credit to Matt and Andy; many hotels could take a lesson from them. The rooms, food, service; the whole place is quality. Also their local knowledge is a great benefit. We will definitely be returning. Mr & Mrs. S. Essex. more

I have just come back from two nights at the Twenty One. My husband and I had a double room and my mum had the single room. From the moment we arrived Matt and Andy were fantastic. Unfortunately my mum had left some of her medical equipment at home and started worrying as I was not with her at the... more

Reviews that were so positive led my wife to choose it for a birthday weekend treat. We were greeted in the most pleasant and welcoming manner by Andy, who gave us tips on best eating, drinking and general retail therapy places in Brighton which we both lived in as students. It is within 5 minutes of Kemptown bars and restaurants,... more

This was a treat for my boyfriends birthday. I was very very pleased with the quality of the guest house. It is immaculately clean and a real home from home. Andy and Matt are lovely and very welcoming. The location is perfect, the decoration of the whole place is superb. We will be returning. more